Publications

Publications

Yu RR, Cheng AT, Lagenaur LA, Huang W, Weiss DE, Treece J, Sanders-Beer BE, Hammer DH, Lee PP, Xu Q, Liu Y. (2008) A Chinese rhesus macaque (Macaca mulatta) model for vaginal Lactobacillus colonization and live microbicide development. J Med Primatol, In Press

Liu X, Lagenaur LA, Lee PP, Xu Q. (2008) Engineering Human Vaginal Lactobacillus for Surface Expression of Two-Domain CD4. Applied and Environmental Microbiology  74,4626-4635

Liu X, Lagenaur LA, Simpson DA, Essenmacher KP, Frazier-Parker CL, Liu Y, Tsai D, Rao SS, Hamer DH, Parks TP, Lee PP, Xu Q.  (2006) Engineered Vaginal Lactobacillus for Mucosal Delivery of the HIV Inhibitor, Cyanovirin-N. Antimicrobial Agents and Chemotherapy  50, 3250-3259

Parks TP, Xu Q, Lagenaur L, Lee PP. (2005) Prevention and treatment of genital tract diseases, Chapter 8. In Probiotics and Prebiotics: Scientific Aspects, G.W. Tannock, ed. (Wymondham, UK: Horizon Scientific Press), pp. 171-194

Chang TL, Chang CH, Simpson DA, Xu Q, Martin PK, Lagenaur LA, Schoolnik GK, Ho DD, Hillier SL, Holodniy M, Lewicki JA, Lee PP. (2003) Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4. Proceedings of the National Academy of Sciences USA 100, 11672-11677

Recent Presentations

Hemmerling A, Harrison W, Park J, Schroeder A, Korn A, Shiboski S, Cohen CR. A Phase I Dose-ranging Safety Trial Testing a Vaginal Probiotic (LACTIN-V) for the Prevention of Bacterial Vaginosis. 35th Annual Scientific Meeting of the Infectious Diseases Society for Obstetrics and Gynecology, Seattle, WA, August 14-16, 2008

Xu Q, Liu X, Lagenaur LA, Liu Y, Yu R, Cheng A, Wells K, Wang J, Parks TP, Hamer DH, Lee PP. Development of a live topical microbicide for women. Microbicides 2008, New Delhi, India, February 24-27, 2008

Yu R, Lagenaur LA, Cheng A, Weiss DE, Treece J, Sanders-Beer BE, Hamer DH, Xu Q, Liu Y. A Chinese rhesus macaque (Macaca Mulatta) model for vaginal Lactobacillus colonization and live microbicide development, Microbicides 2008, New Delhi, India, February 24-27, 2008

Xu Q, Lagenaur L, Liu X, Liu Y, Yu R, Wells K, Tsai D, Sweeney Y, Rao S, Hamer D, Patton D, Parks T, Lee P. Development of a live topical microbicide for women, 2006 International Meeting of the Institute of Human Virology, Baltimore, MD, USA, November 17-21, 2006

Lagenaur LA, Liu X, Wells K, Liu Y, Tsai D, Yu R, Zhu Y, Sweeney Y, Rao S, Hamer D, Parks TP, Patton D, Lee PP, Xu Q. Vaginal lactobacilli for mucosal delivery of the anti-HIV microbicide, Cyanovirin-N. Microbicides 2006 Conference, Cape Town, South Africa, April 23-26, 2006

Xu Q, Lagenaur LA, Liu X, Simpson DA, Essenmacher K, Parker C, Chang CH, Tsai, D, Rao S, Hamer H, Parks TP, Lee PP. Vaginal lactobacilli for mucosal delivery of the anti-HIV microbicide, Cyanovirin-N (CV-N). International Meeting of the IHV, Baltimore, MD, August 29-September 2, 2005

Lagenaur LA, Liu X, Simpson DA, Essenmacher K, Parker C, Chang CH, Tsai, D, Rao S, Hamer H, Parks TP, Lee PP, Xu Q. Development of vaginal lactobacilli for Mucosal Delivery of a topical microbicide, Cyanovirin-N (CV-N). International Meeting of the IHV, Baltimore, MD, August 29-September 2, 2005.

Lee PP, Liu X, Chang C, Lagenaur LA, Liu X, Parks TP, Xu Q. Native vaginal lactobacilli engineered as a delivery vehicle for anti-HIV protein microbicides. Joint Meeting of the 3 Division of the International Union of Microbiological Societies, San Francisco, CA, July 23-28, 2005

Liu X, Lagenaur LA, Frazier-Parker CL Simpson DA, Chang CH., Tsai D, Essenmacher K, Lewicki JA, Parks TP, Lee PP, Xu Q. The Mucoscept approach: a human vaginal isolate of Lactobacillus engineered to produce a potent anti-HIV microbicide. 8th Symposium on Lactic Acid Bacteria, the Netherlands, August 28 - September 1, 2005 

Lagenaur LA, Liu X, Simpson DA, Chang CH, Tsai D, Essenmacher K, Frazier-Parker CL, Lewicki JA, Lee PP, Parks TP, Xu Q. MucoCept: a Live Topical Microbicide for Women. Presented at Alliance for Microbicide Development Annual Meeting, January 13-14, 2005, Washington, DC.

Lewicki JA, Simpson DA, Chang CH, Lagenaur LA, Essenmacher K, Parks TP, Lee PP, Martin PK, Liu X, Xu Q. Native vaginal lactobacilli engineered as a delievery vehicle for anti-HIV protein microbicides. Microbicides 2004, March 28-31, 2004, London, UK

Chang CH, Cheng J, Frankel K, Essenmacher K, Simpson DA, Lagenaur LA, Parks TP, Martin PK, Liu X, Xu Q, Lewicki, JA. Optimizing expression of protein microbicides in lactobacilli: benefits of genomic sequencing, Microbicides 2004, March 28-31, 2004, London, UK